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Chemistry Research at Lycoming College


Summer Chemistry Researchers
http://www.lycoming.edu/chemistrydept/pix/Summer07.jpg
Every summer faculty and students work together in lab doing chemistry research, here is the Summer 2007 group:
(front row, left to right): Charles Mahler, Chriss McDonald, Holly Bendorf, Jeremy Ramsey;
(back row, l to r) Brandon Zarzyczny, Oscar Wheeler, Kyle Totaro, James Grant (not pictured: John Stutzman).


http://www.lycoming.edu/chemistrydept/pix/wheeler07.jpghttp://www.lycoming.edu/chemistrydept/pix/zarzyczny07.jpg
 Left: Oscar Wheeler monitoring a reaction in Dr. Bendorf's lab.
Right: Brandon Zarzyczny working on the Schlenk line in Mahler's lab.


 
  http://www.lycoming.edu/chemistrydept/pix/totaro07.jpghttp://www.lycoming.edu/chemistrydept/pix/grant07.jpg
Left: Kyle Totaro doing column chromatography in Dr. McDonald's lab.
Right: James Grant works with solvent as part of his research with Dr. McDonald.

http://www.lycoming.edu/chemistrydept/pix/pizza07.jpg
Summer researchers meet weekly to present their results, discuss progress, and eat pizza.


Click here for information on Interdisciplinary Research Projects in Chemistry and Biology
supported by the Merck-AAAS Undergraduate Science Research Program. 


Why Do Research?
Previous Student Research Projects
Internships, Independent Studies, Honors Projects, and Summer Research
Faculty Background Information and Research Interests


Internships, Chemistry Research Methods,
Honors, and Summer Research


Many research projects are available at Lycoming College in synthetic organic, organometallic, inorganic, physical, and analytical chemistry. All the Chemistry faculty have projects in which students can involve themselves - or you may have an idea which a faculty member could supervise. Projects may take one of four forms:

1. Internships. These are jointly sponsored by the College and a public or private agency and allow you to earn credit while doing research outside of the school.

2. Chemistry Research Methods. These are taken as a course, but instead of studying a text you can do research in the laboratory under the supervision of a faculty member. Normally a paper is produced and presented orally to the Department for a grade.

3. Honors. If you are an excellent chemistry student, your senior independent studies (see 2) may qualify for departmental honors. This requires you to produce a substantial research paper which is defended orally in front of a committee of three faculty members.

4. Summer Research. Funds are available at Lycoming to pay students to do full-time research over summer vacation. Credit may be earned for such work if you desire.

Student research plays a vital role in preparing for your career. We believe that the undergraduate research program is one of the strengths of the Chemistry Department at Lycoming College.

 


Faculty Background Information and Research Interests


Dr. Holly D. Bendorf, Department Chair, Organic/Organometallic Chemistry
B.S., The Pennsylvania State University
Ph.D., University of California - Los Angeles

Courses: General, Organic, and Organometallic Chemistry
Research: Organic and Organometallic.  Research projects focus on the development of new organometallic reactions and the application of this chemistry to the synthesis of biologically active organic compounds.  Current research focuses on chelation-assisted intramolecular hydroacylation and the synthesis of medium ring heterocycles.

 Further information about Dr. Bendorf's Research

 


Dr. Charles H. Mahler, Physical/Inorganic Chemistry
B.A., The Ohio State University
M.S., Ph.D., Northwestern University
Postdoctoral Fellow, Universität Karlsruhe (TH)

Courses: General, Physical, and Inorganic Chemistry
Research: Inorganic Synthesis, Crystallography, Computational Chemistry. Synthetic research involves making soluble mixed-metal selenides  and the determination of their structures by single-crystal X-ray diffraction. Computational studies have looked at molecular conformational energies and modeling organic molecules for the Chemistry Department's 3-D Molecules page.

 Further Information about Soluble Molybdenum Selenide Chemistry

 Further Information about Computational Chemistry Investigations


Dr. Chriss E. McDonald, Organic Chemistry
B.S., Manchester College
Ph.D., Miami University of Ohio

Courses: General and Organic Chemistry, Spectroscopy
Research: Synthesis of Organic Molecules. Research concentrates on developing new synthetic methodologies for oxygenated functionalities. Ongoing projects include: the use of carbohydrates as starting materials for the synthesis of biologically interesting natural products; oxidation of carbamates by N-halosuccinimides; radical cyclization of masked carbonyl derivatives.
 


Dr. Jeremy D. Ramsey, Analytical Chemistry
B.S., Clarion University of Pennsylvania
Ph.D., The Ohio State University
Postdoctoral Fellow, Oak Ridge National Laboratory

Courses:  General and Analytical Chemistry
Research: 
Miniaturized sensors for the detection of biologically important molecules; Customization of electrode surfaces; New electrode materials for electrochemical analysis; Fast electrophoretic separations; Lab-on-a-chip devices for chemical analysis

Email: ramsey@lycoming.edu

 


List of Chemistry Research Projects


HP: Honors Project; CR:Chemistry Research Methods; IN: Internship;
RA: Research Assistant; IS: Independent Study Project (no longer used, now CR).


Projects are listed in the following order: Student, Type of Project, Project Title, Faculty Advisor.
 

Student

Type of 
Project

Date / Project Title

Faculty 
Advisor

Fall, 2008

Alex Hunter

IS

Organometallic Ruthenium Complexes: Synthesis and Nuclear Magnetic Resonance Studies

 Mahler

John Stutzman

CR

Outgassing of Common Electronic Devices

 Ramsey

Kyle Totaro

CR

A New Ligand for Samarium Diiodide

McDonald

Summer, 2008

Trisha Lindenmuth

RA

Electrodes Modified with Polyoxometalates Using Layer-by-layer Assembly: Applications in Catalysis and Chemical Sensing, REU at Auburn University

 

John Stutzman

RA

Towards Enabling Hydride as a Leaving Group: Carbon Kinetic Isotope Effect on the Hydride Abstraction of 1-Phenylethanol, REU at University of Southern California

 

Oscar Wheeler

CR

Synthesis of an Anion Specific Sensor (REU at the University of Southern Mississippi)

Bendorf

 

 

Spring, 2008

 

James Grant

IS

DiHMPA, a Replacement for HMPA in SmI2 Mediated Radical Reactions

McDonald

Chris Heist

CR

Microfabrication Techniques for Preparing Carbon Microelectrode Arrays

Ramsey

Lauren Raby

CR

Synthesis of Nitrogen-Heterocycles via Hydroacylation: effect of the Nitrogen Protecting Group

Bendorf

 

 

Fall, 2007

 

Christi Groller

CR

The Effect of Organic Monolayers on the Electrochemistry of Dopamine at Carbon Electrodes

Ramsey

Brandon Zarzyczny

CR

Novel Organometallic Ruthenium Complexes and their NMR Spectra

Mahler

 

 

Summer, 2007

 

Nancy Berger

CR

Synthesis of Organometallic Acene Analogues for Applications in Organic Electronics (at the University of Kentucky with Professor Selegue)

Bendorf

James Grant

CR

Samarium Diiodide Radical Reactions Mediated by DiHMPA

McDonald

John Stutzman

RA

Using Amine Terminated Carbon Electrode Surfaces for the Fabrication of Glucose Sensors

Ramsey

Kyle Totaro

RA

A New Strategy for the Synthesis of FGAR: Amidine and Glucose-Derived Sugars

McDonald

Oscar Wheeler

RA

Synthesis of Nitrogen-Containing Hydroacylation Substrates

Bendorf

Brandon Zarzyczny

RA

Nuclear Magnetic Resonance Studies of Organometallic Ruthenium Complexes

Mahler

 

 

Spring, 2007

 

Dan DiRocco

HP

Synthesis of Biologically Active Benzothiepinones

Bendorf

John Stutzman

RA

The Effect of Polishing Techniques on Electrochemical Kinetics at Carbon Electrodes

Ramsey

Jamie Tribo

CR

Preparation of Enzyme Modified Carbon Electrodes via Diazonium Derivatization

Ramsey

 

 

Fall, 2006

 

Sara Bartlett

CR

Synthetic and Computational Studies of Pentamthylyclopentadienyl Ruthenium Phosphine Complexes

Mahler

Dan DiRocco

CR

Tandem Hydroacylation-Michael Addition:  Synthesis of Aminomethylbenzothiepinones

Bendorf

Corey Mitchell

CR

Generalization of the Silylamide Component in the Lewis Acid Mediated Amidation of Carbohydrates

McDonald

Melissa Pownall

CR

Electrochemistry at Glassy Carbon Electrodes Derivatized by Oxidation of Arylacetates

Ramsey

Andrew Shurer

CR

Synthesis of Benzazepinones via Intramolecular Hydroacylation

Bendorf

 

 

Summer, 2006

 

Brittany Austin

CR

The Synthesis of 1ā3 Branched Poly-Urea Newkome-Type Dendrons and Dendrimers (Research conducted at the University of Akron with Dr. Newkome)

Bendorf

Nancy Berger

RA

Synthesis of Novel N-Heterocyclic Carbenes for use in Olefin Metathesis, REU at the University of Southern Mississippi

 

Scot Bower

CR

A New Method for the Conversion of Lactols to Amidoacetals

McDonald

Dan DiRocco

RA

Industrial Chemistry Internship, Merck Pharmaceutical Company

 

Katherine Kressler

CR

Using Electrochemistry to Attach and Remove Molecules to Glassy Carbon Electrodes

Ramsey

Erika Pfaunmiller

CR

A New Synthesis of Glycosylamides

McDonald

Andrew Shurer

RA

Efforts Toward Synthesis and Biological Evaluation of Receptor Selective FTY720 Analogs, REU at the University of Virgina

 

Jamie Tribo

RA

Industrial Chemistry Internship,

 

 

 

Spring, 2006

 

Josemar Castillo

HP

Synthesis and Characterization of New Soluble Transition-Metal Selenides with Phosphine Ligands

Mahler

Dan DiRocco

RA

Tandem Hydroacylation-Michael Addition: Synthesis of Pharmaceutical Precursors

Bendorf

Stephanie Falcioni

CR

Modifying the Surface of a Glassy Carbon Electrode via Electrochemistry and Investigating the Effect on the Electron Transfer Kinetics of Dopamine

Ramsey

Tim Hartingh

CR

A New Route to Glycosylamides and Application to the Synthesis of FGAR   

McDonald

Kim McDowell

CR

Synthesis and NMR Studies of Ruthenium Organometallic Compounds

Mahler

Andrew Shurer

RA

Synthesis of Benzazepines by Chelation-Assisted Intramolecular Hydroacylation      

Bendorf

Lindsey Welch

CR

Synthesis of Medium-Ring Carbocycles by Chelation-Assisted Intramolecular Hydroacylation                                                

Bendorf

 

 

Fall, 2005

 

Hans Bottesch

CR

Synthesis and NMR Studies of Ruthenium Organometallic Compounds

Mahler

Josemar Castillo

CR

Synthesis and Characterization of New Soluble Transition-Metal Selenides with Phosphine Ligands

Mahler

Chrissy Caroselli

CR

Synthesis of Medium-Ring Carbocycles by Chelation-Assisted Intramolecular Hydroacylation                                                

Bendorf

Dan DiRocco

RA

Tandem Hydroacylation-Michael Addition: Synthesis of Pharmaceutical Precursors

Bendorf

Kelly Howerter

CR

A New Route to Glycosylamides and Application to the Synthesis of FGAR   

McDonald

Andrew Shurer

RA

Synthesis of Benzazepines by Chelation-Assisted Intramolecular Hydroacylation      

Bendorf

 

 

Summer, 2005

 

Karissa Capitan

RA

Internship, PPL Susquehanna (Nuclear Power Plant), LLC

 

Josie Castillo

RA

Separation, Characterization, and Functionalization of the Triscandium Nitride Metallofullerene ScN@C78, REU, Clemson University

 

Dan DiRocco

RA

Industrial Chemistry Internship, Merck Pharmaceutical Company

 

Anne Marie DiSante

CR

Synthesis and Characterization of New Soluble Transition-Metal Selenides with Phosphine Ligands

Mahler

Kelly Howerter

RA

Forensics Laboratory Internship, Federal Bureau of Investigation

 

Jillian Johnson               

IN 

The Synthesis of Pentaerythritol-Based Polyesters, Internship with Croda Chemical Company in Mill Hall, PA

McDonald

Erin Peters

CR

Computational Chemistry Investigations Using the CAChe Software Package

Mahler

Lauren Watkins

IN

Internship with Osram Sylvania, in Towanda, PA

Mahler

 

 

Spring, 2005

 

Dan DiRocco

RA

Synthesis of Aminomethylbenzothiepinones via Tandem Hydroacylation - Michael Addition

Bendorf

Andrew Shurer

RA

Synthesis of Hydroacylation Substrates

Bendorf

 

 

Fall, 2004

 

Dan DiRocco

RA

Tandem Hydroacylation-Michael Addition: Synthesis of Pharmaceutical Precursors

Bendorf

Olivia English

CR

Synthesis and Characterization of New Soluble Transition-Metal Selenides with Phosphine Ligands

Mahler

Laura Lockard

CR

Novel Samarium Diiodide Mediated 5-exo-trig and 6-exo-trig Cyclizations of Sulfoxide Precursors

McDonald

Michelle Morone

CR

Benzazepine Synthesis via Rhodium-Catalyzed Hydroacylation

Bendorf

Damien Reali

CR

The Use of Methyl Phenyl Sulfoxide as a Reagent for Construction of Carbon-Carbon bonds Under Radical Conditions 

McDonald

 

 

Summer, 2004

 

Dan DiRocco

RA

Tandem Hydroacylation-Michael Addition: Synthesis of Pharmaceutical Precursors

Bendorf

Dylan Dupuis

IN

R and D Sample Stability Project at Chanel Inc.

Mahler

Olivia English

RA

Synthesis and Characterization of New Soluble Transition-Metal Selenides with Phosphine Ligands

Mahler

Kelly Howerter

RA

The SmI2-mediated Cyclization of Pummerer Rearrangement Products: Optimization of the Radical Cyclization of Unsaturated a-Trifluoroacetoxy Sulfides with Samarium Iodide

McDonald

Erin Karschner

CR

An Enzyme-Coupled Spectrophotometric Assay for S-Adenosylhomocysteine Nucleosidase and S-Adenosylmethionine Methyltransferases (at Washington State University with Dr. Sunny Zhou)

Bendorf

Theresa LaBarte

CR

Intramolecular Hydroacylation of Nitrogen-Containing Substrates: Synthesis of Azepines

Bendorf

 

 

Spring, 2004

 

Dan DiRocco 

RA  

Tandem Hydroacylation-Michael Addition: Synthesis of Pharmaceutical Precursors

Bendorf

Jennifer Clark

CR

Analysis of Ergosterol in Plant Leaf Material: Method Development and Improvement

Franz

JJ Manikowski

HP

Exploration into the Novel Generation of Carbon Radicals

McDonald

Lisa Stutzman 

CR  

Synthesis of Medium Ring Nitrogen Heterocycles Using Chelation-Assisted Intramolecular Hydroacylation

Bendorf

 

 

Fall, 2003