Spectroscopy and Molecular Structure
Fall 1997 Syllabus
Instructor: Office: Phone: Home Phone: Dr. Holly D. Bendorf 209 HBC 4365 327-2888Course Schedule:
Lecture: MWF 9:00 - 9:50 am Room 203 Lab Sections: R 7:45 - 11:35 am Room 239Office Hours: By appointment or walk-in.
Course Description: We will examine the modern techniques for the structural elucidation of organic molecules, including IR, NMR, UV, and mass spectrometry. Both theory and applications will be addressed with an emphasis on problem-solving.
Text and Materials:
"Spectrometric Identification of Organic Compounds" 5th edition, Silverstein, Bassler, and Morrill, 1991.
Bound laboratory notebook (Freeman).
Lab deposit ($10.00 at lab check-in, will be returned, minus breakage charges, at check-out).
Safety glasses or goggles.
Quizzes 75 pts (10%) Assignments 70 pts (10%) Class Participation 20 pts (3%) and Attendance Exams 300 pts (40%) Laboratory 135 pts (17%) Final 150 pts (20%)Total points: 750
All exams will be given on Thursdays, during the lab period. These dates will not be changed.
Quiz dates are tentative and may vary depending on our progress with the lecture material. If we need to move a quiz, I will make every effort to give at least a week's notice.
The homework assignments are listed on the day that they are due. You should work on the assignments as we cover the material in class. Although the assignments consist of only a few problems, please realize that some spectral problems may require a considerable amount of analysis (and time). Also, I have found that even simple spectral problems can become incredibly difficult if I have not had enough sleep or can not concentrate well for some reason.
One final note:
Every chemist develops his or her own method for solving problems. This is especially true in spectroscopy. The only way anyone ever becomes proficient at solving spectral problems is by working lots of problems, making the occasional mistake and learning from those mistakes. Try not to get frustrated if the problems seem kind of tough at first--with patience and practice they get a lot easier. Most importantly, try to have fun!! What other class gives you credit for working puzzles?!?!
THIS SCHEDULE STILL UNDER CONSTRUCTION....
Week Dates Topic Q or E Reading Assignment Homework Problems 1 25-Aug Intro. to structural determination Chapter 1 27-Aug combustion analysis and DU calculation 2.6 29-Aug Mass Spec: instrumentation and theory 2.1-3 2 1-Sep High resolution mass spec., the molecular ion peak 2.4-6 3-Sep Fragmentation patterns... 2.7-10 5-Sep ...of classes of organic compounds 2.1 3 8-Sep problems 2.1-8 10-Sep CI mass spec 12-Sep Infrared Spectroscopy: theory, instrumentation Q 3.1-4 4 15-Sep Functional group absorptions... 3.5-6 17-Sep ...and interpretation 3.6 19-Sep as above 3.6 5 22-Sep problems 3.1-12 24-Sep NMR theory Thursday 4.1 26-Sep Instrumentation and practical considerations Exam 4.2 6 29-Sep Chemical shift: measurement and influencing factors 4.3 1-Oct Chemical shift: correlation to functional groups Appendix B 3-Oct no classes 7 6-Oct Integrations, simple spin-spin coupling 4.4 4.1, handout 8-Oct protons on heteroatoms 4.5-6 10-Oct the coupling constant, karplus curve Q 4.11 8 13-Oct chemical and magnetic equivalence 4.7-10, 12 15-Oct decoupling techniques 4.13-14 17-Oct problems 9 20-Oct problems 4.2-5 and Ch. 9(TBA) 22-Oct problems Thursday 24-Oct 13C NMR: intro., practical considerations Exam 5.1,2,4,6 10 27-Oct chemical shifts 5.3 29-Oct chemical shift calculations 5.5 31-Oct problems 5.1-6 and Ch. 9(TBA) 11 3-Nov problems 5-Nov problems 7-Nov Advanced NMR techniques: DEPT quiz 6.1,3 12 10-Nov HETCOR 6.3 12-Nov COSY 6.2 14-Nov NOE difference 6.5,6 13 17-Nov Dynamic NMR 6.2-4 and Ch. 9(TBA) 19-Nov problems Thursday 21-Nov UV: theory and sample prep. Exam 7.1-3 14 24-Nov Interpretation of UV 7.4 26-Nov No classes 28-Nov No classes 15 1-Dec Interpretation of UV 7.4 3-Dec Techniques for determining absolute stereochemistry: 7.1-3 and Ch. 9(TBA) 5-Dec polarimetry, chiral shift rgts., ORD/CD Finals Week The final exam will be administered on the date and time assigned by the registrar. No Exceptions!
Last updated August 28, 1997.
The URL for this page is http://lyco2.lycoming.edu/dept/chem/fall1997/442syl.htm