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Mass Spectrometry


Mass Spectrometry is used to determine the molecular weight of a given compound.  It can also be used to determine the connectivity (that is, how the molecule is hooked together) of a compound.  In this technique, the compound to be analyzed is ionized, the resultant ion (and fragment ions) are separated in magnetic and/or electric fields, and then ordered on the basis of mass to charge ratio.  Our mass spectrometer (Thermo Polaris Q) is interfaced to a gas chromatograph (Thermo Trace GC) so we can analyze mixtures.  The GC will separate the mixture and the MS will provide structural information for each compound. We obtained the GC/MS in 2001 at a cost of about $85,000, with the help of grants from the National Science Foundation,* Dreyfus Foundation, and Lycoming College. The GC/MS also has an autosampler to allow us to run samples from every student in a class overnight.
 
 
Jeff Musselman is analyzing a new compound by GC-MS
 

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Last updated September 13, 2007. * This material is based upon work supported by the National Science Foundation under Grant No. 0087767
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