While every effort has been made to make sure this electronic syllabus is error-free, it is not official.
The definitive source of course information remains the original (paper) syllabus distributed in class.

Spring 1996, Brief Organic, Lycoming College

Course description - This course is designed to introduce the student to the chemistry of organic compounds and survey various classes of biomolecules with regard to their structure and biological activity. The laboratory component of the course is designed to reinforce topics discussed in the lecture as well as to examine some basic techniques of the two disciplines.

Faculty                       Responsibilities                   Office
Dr. Chriss McDonald           lectures, lab, recitations         HBC 233 
Mrs. Henriette Evans          lab                                HBC G28 

321-4186 (work), 433-4493 (home, call up to 10 pm [no kidding]), or E-mail (mcdonald@lycoming.edu)

Texts and other stuff
a. Fundamentals of General, Organic, and Biochemistry, Fifth Edition by John Holum*
b. Chemistry 115 Lab Manual, by McDonald*
c. Bound laboratory notebook by Freeman*
d. Lab safety glasses*
e. Calculator (add, subtract, multiply, divide, logs)
f. Lab deposit, $10.00 at lab check-in cash only (refundable upon check- out)

* Available at the bookstore

Course format
Lectures - MWF, 11:30 - 12:20, HBC G11. Attendance required.

Recitations - Thursday, 7:45 - 8:35 am and 1:00-1:50 pm, HBC G09. The primary method for evaluating chemistry students in testing situations is to have them do problems. Here we will practice the types of problems you will see on tests and quizzes. Attendance expected. I will not take attendance but will use some of the examples discussed in recitation as exam and quiz questions. I have found that, on the average, students who attend recitation in my classes get one full letter grade higher, than students who don't attend.

Assigned homework - Problems designed to enhance your understanding and prepare you for testing situations. A key will be posted in the secretary's office. Homework will not be collected. A large chunk of recitation will be devoted to working these problems.

Laboratory -X: 8:45 - 11 :35 am, Tuesday (Evans), Y: 2:00-4:50 pm Thursday (McDonald), Z: 2:00 - 4:50 PM, Thursday (McDonald), HBC 220, 239. Attendance required. Makeups for missed labs are usually not possible. Here you will experience what chemists actually do. Your lab work will be evaluated as described on the lab syllabus as well as on the lecture exams. Approximately 5% of each exam will be drawn from the labwork. A lab syllabus will be distributed the first week of lab. Make sure and show up for prelab the first week with your lab manual and lab deposit (cash only).

Grading scheme
a. The final grade is based on the number of points obtained out of a possible 650 points. The points will be distributed as follows:

     intro/biog.                                          10 points (02%)
     quizzes                                              70 points (11%)
     hour exams                                          300 points (45%)
     final exam                                          100 points (15%)
     laboratory                                          180 points (27%)
     total                                               650 points (100%)
b. Assignment of letter grades is based on the following scale: 594 - 660 A, 528 -593 B, 462 - 527 C, 396 - 461 D, < 396 F.

c. A word about learning chemistry. Studying chemistry is hard work for most people (this is certainly true for me). I would recommend you work on the lecture material one hour per day outside of class for starters. Once you see how things are going this amount can be adjusted up or down depending on your needs (I suggest significantly up prior to exams). If you are having trouble, make sure and see me and I'll do what I can to help you (I'm pretty easy to talk to so don't hesitate to come in). A tutor is also available. Her name is Gail Forsht and she tutors from 7:30 to 8:30 on Monday and Wednesday nights. You will be responsible for all of the material listed on the following schedule for the indicated exams and quizzes. It is not sufficient to learn the information from the lecture alone, you are expected to have read and thought about the assignment prior to the lecture. We must cover a large amount of material so our pace must be geared towards those who are ready to learn. The exams will be somewhat cumulative in the sense that we often need to know the earlier material to comprehend the latter.

Policy on attendance
Attendance at quizzes and exams is mandatory. Makeups will be administered only if I deem the reason for absence to be legitimate and I am made aware of the absence beforehand. Each documented, unexcused lecture absence will cost you one point from your total.


DATE   TOPIC                                     READING ASSN..   Q/E
1/8    introduction                              12.1
1/10   bonding and hydrocarbon structure         12.2,3, 5.2
1/12   nomenclature and functional groups        12.4-6, 5.4
       (last day to drop)

1/15   more nomenclature, 
       alkane physical properties                12.5,6, 5.6, 6.6
1/17   alkane rxns                               12.7, 3.3
1/19   alkene nomenclature                       13.1-3           quiz 1

1/22   alkene addition rxns                      13.4, 9.1
1/24   more of same                              13.4
1/26   arenes and substitution rxns              13.7             quiz 2

1/29   alcohol properties and nomenclature       14.1,2, 6.6, 7.2
1/31   alcohol rxns                              14.3
2/2    thiols                                    14.6             quiz 3

2/5    aldehyde/ketone nomenclature & properties 15.1,2
2/7    A/K redox behavior                        15.3,4
2/9    exam 1                                                     exam 1

2/12   A/K and alcohols                          15.5
2/14   carboxylic acid nomenclature/acidity      16.1,2
2/16   esters, structure and rxns                16.4,5

2/19   amines, structure and basicity            17.1,2
2/21   amides structure and rxns                 17.3
2/23   penicillin, nylon                         17.3             fatquiz 4

2/26   spri                                      -
2/28       ng b                                  -
3/1            reak                              -

3/4    enantiomerism                             18.1
3/6    diastereomerism                           18.2
3/8    exam 2                                    -                exam 2

3/11   biochemistry overview                     19.1
3/13   monosaccharWe structure                   19.2-4
3/15   di- and polysaccharides                   19.5,6

3/18   fatty acids and esters                    20.1,2
3/20   amino acids                               21.1
3/22   protein structure                         21.2-7           fatquiz 5

3/25   as above                                  21.2-7
3/27   enzymes                                   22.1
3/29   how enzymes work                          22.2-4           quiz 6

4/1    medical applications of enzymes           22.5
4/3    cell structure                            24.1
4/5    good friday                               -

4/8    exam 3                                    -                exam 3
4/10   nucleic acid structure                    24.2
4/12   dna replication                           24.2

4/15   rna and transcription                     24.3
4/17   translation                               24.3,4
4/19   the hiv-1 virus and biochemical warfare   24.5

4-22 thru 4/25 final exam week

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