Biology: Assistant Professor
Neuroscience: Assistant Professor
Special Interest: Anatomy; neuroscience; dopaminergic neurotransmission; neurophysiology; development
Professor Kat Bartlow’s work focuses on the way neurons (brain cells) send and receive signals using chemicals called neurotransmitters. Professor Bartlow is particularly interested in dopamine, which is a major neurotransmitter in many animals. In mammals, dopamine affects the activity of many neurons and is vital for voluntary movement and motivated behavior. Many neurological disorders, including Parkinson’s disease, addiction, ADHD and schizophrenia, involve dysregulation of dopaminergic neurotransmission.
The major scientific questions that interest her include:
- How do dopaminergic systems develop?
- What is the function of dopaminergic signaling in animals distantly related to humans?
- How is the release and uptake of dopamine affected by specific genes and proteins expressed in dopaminergic neurons?
To help answer these questions, she performs laboratory research in molecular biology, cell biology and physiology using a wide variety of preparations including rodent brain slices, cultured human cells and parasitic flatworms. Students working in her lab will have opportunities to learn a wide variety of exciting techniques including cell culture, fast-scan cyclic voltammetry, extracellular electrophysiology, and the design and analysis of next-generation sequencing experiments.
Professor Bartlow enjoys teaching neuroscience as much as she enjoys studying it and takes personal delight in getting her students just as fired up about the nervous system as she is.
Publications (some published under her birth name of K. Salerno)
Publications In Revision
Bumpus EN*, Runyan KR*, Weitekamp SL*, Bartlow KM. Monoaminergic signaling regulates swimming behavior in cercariae of Proterometra macrostoma (Trematoda:Azygiidae). Accepted pending revisions, Journal of Parasitology.
2015 Taylor IM, Nesbitt KM, Walters SH, Varner EL, Shu Z, Bartlow KM, Jaquins-Gerstl AS, Michael AC. Kinetic diversity of dopamine transmission in the dorsal striatum. J Neurochem. 133(4): 522-31.
2013 Salerno KM, Jing X, Diges CM, Davis BM, Albers KM. TRAF family member-associated NF-kappaB activator (TANK) expression increases in injured sensory neurons and is transcriptionally regulated by Sox11. Neuroscience 231: 28-37.
2012 Salerno KM, Jing X, Diges CM, Cornuet PK, Glorioso JC, Albers KM. 2012. Sox11 modulates brain-derived neurotrophic factor expression in an exon promoter-specific manner. J Neurosci Res. 90(5): 1011-9.
2009 Jankowski MP, McIlwrath SL, Jing X, Cornuet PK, Salerno KM, Koerber HR, Albers KM. 2009. Sox11 transcription factor modulates peripheral nerve regeneration in adult mice. Brain Res. 1256: 43-54.
2004 Jones RJ, Smith SM, Gao YT, DeMay BS, Mann KJ, Salerno KM, Salerno JC. 2004. The function of the small insertion in the hinge subdomain in the control of constitutive mammalian nitric-oxide synthases. J Biol Chem. 279(35): 36878-83.
2003 Salerno JC, Eifert CL, Salerno KM, Koretz JF. 2003. Structural diversity in the small heat shock protein superfamily: control of aggregation by the N-terminal region. Protein Eng. 16(11): 847-51.
Other recognitions and interests
Professor Bartlow enjoys traveling to other countries, hiking, and trail running. She also loves to cook and is looking forward to inviting her research students over for the occasional lab dinner.
Society for Neuroscience
American Physiological Society
Faculty for Undergraduate Neuroscience
Human Anatomy and Physiology Society