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Mass Spectrometry


Mass Spectrometry is used to determine the molecular weight of a given compound.  It can also be used to determine the connectivity (that is, how the molecule is hooked together) of a compound.  In this technique, the compound to be analyzed is ionized, the resultant ion (and fragment ions) are separated in magnetic and/or electric fields, and then ordered on the basis of mass to charge ratio.  Our mass spectrometer (Thermo Finnigan Polaris Q) is interfaced to a gas chromatograph (Thermo Finnigan Trace GC) so we can analyze mixtures.  The GC will separate the mixture and the MS will provide structural information for each compound. We obtained the GC/MS in 2001 at a cost of about $85,000, with the help of grants from the National Science Foundation, Dreyfus Foundation, and Lycoming College. The GC/MS also has an autosampler to allow us to run samples from every student in a class overnight.
 
 
Jeff Musselman is analyzing a new compound by GC-MS
 

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Last updated October 14, 2004.
The URL for this page is http://www.lycoming.edu/chem/tour/inst4.htm